By William Llewelly
William Llewellyns anabolics has been the main depended on anabolic steroid info source for greater than a decade. thought of the definitive reference guide on body- and performance-enhancing medications, this publication contains an intensive evaluation of the historical past, availability, medical program, and functional use of anabolic/androgenic steroids, human progress hormone, insulin, anti-estrogens, diuretics, reductase inhibitors, thyroid hormones, stimulants, and quite a few different functionality medicines. the most recent (9th) variation has been absolutely up to date, and is the main finished and informative model of this mythical e-book ever released.
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Extra info for Anabolics (9th Edition)
The 17-methyl group is well understood at this point as we have discussed it with many steroids, however, the 2-hydroxymethylene group is not seen on any other commercial: steroid. We do know that this group greatly enhances anabolic potency by! increasing the stability of the 3-keto group, and that the configuration of this substituent also appears to allow this steroid to bind and activate the estrogen receptor. HOHC o~ Oxymetholone (+2 hydroxymethylene; 17alpha-methyl) OH i Stanozolol is a potent anabolic steroid, owing to the fact that the 3-2 pyrazol grou~ creates a stable configuration off the A-ring that allows for androgen receptor binding (this steroid is one of the few that does not possess an actual 3-ket~ group).
Anabolic steroids remain in use for osteoporosis in many other nations, however, and are still prescribed to varying patient populations including men, women, and the elderly. The significant loss of lean body mass can present its own set of health issues. 83 Severe weight loss during recovery from surgery or illness may also measurably delay or complicate the recovery phase. 84 In the most severe cases, an ability of the patient to maintain acceptable lean body mass can be the key determining factor in recovery.
Aside from dihydrotestosterone and Proviron® (mesterolone), which undergo rapid enzymatic reduction in muscle tissue to inactive metabolites, the remaining anabolic/androgenic steroids seem to bind with near equal affinity to receptors in both tissues. They seem to be relatively IIbalanced" in effect. This study also discusses the unique activity of testosterone and nandrolone compounds, which are good substrates for the Sa-reductase enzyme found in androgen target tissues (such as the prostate), and seem to provide the most notable variance between anabolic and androgenic effect in humans due to this local metabolism.
Anabolics (9th Edition) by William Llewelly